How do muscarinic agonists treat overactive bladder?

Muscarinic agonists serve a specific role in the treatment of overactive bladder by addressing the bladder's activity through the stimulation of muscarinic receptors, particularly the M3 subtype, which promotes contraction of the detrusor muscle, facilitating micturition. However, the effect of muscarinic agonists directly correlates with the restoration of normal bladder function rather than simply decreasing pressure or contractions.

In the context of the question, the answer indicates that muscarinic agonists help to decrease bladder pressure and contractions which is reflective of their regulation on improving bladder function by facilitating a controlled pattern of contractions during urination. By maintaining a balance in bladder activity, these agonists help reduce symptoms associated with overactivity, which can manifest as urgency and frequency of urination.

Therefore, the focus of muscarinic agonists lies in enhancing the coordination of bladder contractions, thus reducing inappropriate contractions that lead to the symptoms of overactive bladder.