What are common adverse drug events associated with up to 5 mg of atropine?

Study anticholinergic agents for pharmacology with interactive components and detailed explanations. Hone your skills and prepare effectively for your examination in pharmacology!

Atropine is an anticholinergic agent that works by blocking the action of acetylcholine at muscarinic receptors. When administered, particularly at doses such as 5 mg, it can lead to several characteristic side effects due to its action on the body’s parasympathetic nervous system.

One of the most common adverse drug events associated with atropine is dry mouth, which occurs because the drug reduces salivary gland secretion. This is an expected reaction due to the drug's anticholinergic properties.

Blurred vision can also occur because atropine dilates the pupils (mydriasis) and paralyzes the ciliary muscle (cycloplegia), which disrupts the eye’s ability to focus properly. This visual disturbance is commonly reported with atropine use.

Tachycardia is another significant effect, as atropine increases heart rate by inhibiting the vagal tone on the sinoatrial node of the heart. This can lead to a palpitation sensation and may be a critical effect of the drug, especially in clinical scenarios where bradycardia is present.

Collectively, these three effects—dry mouth, blurred vision, and tachycardia—are well-documented adverse reactions associated with atrop

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