What is a common adverse effect associated with the use of Succinylcholine?

Succinylcholine is a depolarizing neuromuscular blocker commonly used for rapid sequence intubation and as an adjunct in general anesthesia. One of the most frequently reported adverse effects of succinylcholine is muscle soreness or myalgia. This is particularly notable after surgery, especially when succinylcholine is used for rapid muscle relaxation during intubation. The muscle soreness occurs due to the initial depolarization and subsequent muscle contractions that can lead to discomfort in the muscles.

This effect can be more pronounced in situations where succinylcholine is administered repeatedly or in patients who have significant muscle mass or engage in vigorous activity. The soreness typically occurs in the muscles that have been relaxed during the procedure but can have widespread effects.

Understanding this adverse effect is important for healthcare professionals to anticipate patient discomfort in the postoperative period and manage pain appropriately.