What is one reason to avoid prescribing Atropine to children?

Atropine is an anticholinergic agent that can have a range of effects due to its action on the central and peripheral nervous systems. One important reason to avoid prescribing Atropine to children is that they can be particularly sensitive to its effects. This heightened sensitivity can lead to more pronounced side effects or adverse reactions when compared to adults. Children may not tolerate the medication well, and the central nervous system effects, such as sedation or agitation, can be more significant in this population.

In general, children have immature organ systems and differing pharmacokinetic profiles, which can influence how medications work in their bodies. Sensitivity may also vary with age, meaning younger children may experience worsened effects or toxicity with doses that are typically safe for older children or adults. Therefore, caution is warranted when considering Atropine for pediatric patients, emphasizing the need for careful consideration of the risks versus benefits in treating this population with anticholinergic agents.