What specific effect does atropine have on sweating?

Atropine is an anticholinergic agent that inhibits the action of acetylcholine at muscarinic receptors, particularly in the peripheral nervous system. One of the key areas where acetylcholine has an important role is in the activation of sweat glands.

By blocking the muscarinic receptors, atropine effectively reduces the stimulation of these glands, leading to decreased sweating. This is especially relevant in situations where anticholinergic effects are deliberately desired, such as to manage excessive sweating (hyperhidrosis) or to prevent sweat production during surgical procedures.

Therefore, atropine's effect on sweating is characterized by a significant reduction, which makes the correct answer C.