Which drug is used as an antimuscarinic transdermal patch for motion sickness?

The drug used as an antimuscarinic transdermal patch for motion sickness is scopolamine. This medication is particularly effective in preventing nausea and vomiting associated with motion sickness due to its ability to block the action of acetylcholine at muscarinic receptors in the vestibular system and the area postrema of the brain, which helps to reduce the symptoms of motion-induced nausea.

Scopolamine is often applied via a transdermal patch, providing a sustained release of the drug over time. This method of delivery is advantageous for conditions like motion sickness, where continuous medication is required to prevent symptoms during travel. By inhibiting parasympathetic nervous system activity, scopolamine helps to mitigate the effects of motion on the body’s balance systems.

The other drugs mentioned do not serve as transdermal patches for motion sickness. For example, ipratropium is primarily used as a bronchodilator in respiratory conditions, tiotropium is also a long-acting bronchodilator, specifically for chronic obstructive pulmonary disease (COPD), and atropine has different uses, such as increasing heart rate in bradycardia and as an antidote for organophosphate poisoning, but is not indicated for motion sickness in a patch form.