Which organ system can be significantly affected by anticholinergic agents?

Anticholinergic agents primarily work by blocking the action of acetylcholine at muscarinic receptors, which can have a profound impact on the cognitive system. Acetylcholine is crucial for various cognitive functions, including memory, attention, and learning. When anticholinergic agents are administered, they can lead to symptoms such as confusion, impaired memory, and even delirium, especially in older adults or those predisposed to cognitive decline.

This impact on cognitive function is particularly relevant in geriatric populations where high anticholinergic burden can exacerbate cognitive impairment and increase the risk of dementia. Other organ systems may also experience effects from anticholinergic agents, such as decreased digestive secretions or changes in heart rate; however, the cognitive effects are notably significant and often a primary concern in clinical settings.